Quantitative Liver Function Tests: A Realizable Goal?

Pharmacogenomics of hypertension: a realizable goal?

It is common clinical experience that individual patients vary in their response to different types of anti-hypertensive drugs. The best recognized example of this is the much poorer response of black subjects to angiotensin-converting enzyme (ACE) inhibitors compared with that of Caucasians. However, even within a relatively homogeneous group, individual responses vary greatly. This was shown ...

Effect of Ramadan Fast on Liver Function Tests

Abnormal Liver Function Tests

LFTs are not specific to specific systems or disease processes, yet abnormalities may indicate significant or serious disease. Interpreting abnormal LFTs and trying to diagnose any underlying liver disease is a common scenario in Primary Care. Single abnormalities in LFTs are difficult to localise and diagnose [2] . However, the pattern of abnormalities tests helps determine origin of the issue...

Liver Function Tests

The liver may be regarded as a system of branching bile ducts which terminate in numerous blind tubules, the bile canaliculi. The walls are formed by the liver cells, which are externally in contact with the capillaries of the portal venous system and the hepatic arterial system: these cells are homogeneous and show no obvious signs of differentiation or specialization. But in spite of its anat...

Abnormal Liver Function Tests:

Serum levels of aspartate aminotransferase and alanine aminotransferase that exceed 1000 IU/L indicate acute viral hepatitis (A, B and, rarely, C), acute drug toxicity (eg, acetaminophen overdose or isoniazid hepatotoxicity), or ischemic liver injury. In chronic hepatitis (ie, hepatitis B or C or autoimmune), values range from mildly elevated to usually less than 400 IU/L. Elevated levels of al...